1-(2-Aminoethyl)piperidine , 98% , 27578-60-5

Synonym(s):
2-Piperidinoethylamine

CAS NO.：27578-60-5

Empirical Formula: C7H16N2

Molecular Weight: 128.22

MDL number: MFCD00006516

EINECS: 248-540-8

PRODUCT Properties

• Melting point: 67-70 °C(Solv: ligroine (8032-32-4); dichloromethane (75-09-2))
• Boiling point: 186 °C(lit.)
• Density: 0.899 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.473(lit.)
• Flash point: 136 °F
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• form: Liquid
• pka: pK1: 6.38;pK2: 9.89 (30°C)
• color: Clear colorless to yellow
• Water Solubility: Partly miscible in water.
• Sensitive: Air Sensitive
• BRN: 103469
• CAS DataBase Reference: 27578-60-5(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidineethanamine(27578-60-5)

Description and Uses

1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

Safety

• Symbol(GHS): GHS02,GHS05
• Signal word: Danger
• Hazard statements: H226-H314
• Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
• Hazard Codes: C,Xi
• Risk Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2734 8/PG 2
• WGK Germany: 3
• Hazard Note: Irritant
• HazardClass: 3
• PackingGroup: III
• HS Code: 29333990