Aspartame , 98% , 22839-47-0
Synonym(s):
Aspartame;Asp-Phe methyl ester;Asp-Phe-OMe;N-(L -α-Aspartyl)-L -phenylalanine methyl ester;Anti-cmer
CAS NO.：22839-47-0
Empirical Formula: C14H18N2O5
Molecular Weight: 294.31
MDL number: MFCD00002724
EINECS: 245-261-3
| Pack Size | Price | Stock | Quantity |
| 1G | RMB24.00 | In Stock |
|
| 5G | RMB25.60 | In Stock |
|
| 25G | RMB41.60 | In Stock |
|
| 100g | RMB88.80 | In Stock |
|
| 500g | RMB372.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 242-248 °C |
| alpha | 15.5 º (c=4, 15N formic acid) |
| Boiling point: | 436.08°C (rough estimate) |
| Density | 1.2051 (rough estimate) |
| refractive index | 14.5 ° (C=4, 15mol/L Formic Acid) |
| storage temp. | 2-8°C |
| solubility | Sparingly soluble or slightly soluble in water and in ethanol (96 per cent), practically insoluble in hexane and in methylene chloride. |
| form | Powder |
| pka | pKa 3.19±0.01 (H2O t=25.0 I=0.100(NaCl))(Approximate);7.87±0.02(H2O t=25.0 I=0.100(NaCl))(Approximate) |
| color | White |
| PH | pH(8g/l, 25℃) : 4.5～6.0 |
| Odor | odorless with a sweet taste |
| Water Solubility | Soluble in formic acid, dimethyl sulfoxide. Sparingly soluble in water and ethanol. |
| Merck | 14,839 |
| BRN | 2223850 |
| Sequence | H-Asp-Phe-OMe |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | IAOZJIPTCAWIRG-QWRGUYRKSA-N |
| LogP | 0.542 (est) |
Description and Uses
Aspartame is a synthetic non-caloric sweetener that is metabolized to phenylalanine, aspartic acid, and methanol in the gut. Aspartame (80 mg/kg per day for 90 days) increases plasma alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity, induces hepatocyte degeneration and leukocyte infiltration in the liver, and reduces hepatic levels of reduced glutathione (GSH), oxidized glutathione (GSSG), and γ-glutamylcysteine (γ-GC) in mice. Formulations containing aspartame have been used as sweetening agents and flavor enhancers in foods and beverages.
Aspartame in powder form for limited uses such as cereals, powdered drinks, and chewing gum. When aspartame is used in baked goods and baking mixes, it should not exceed 0.5% by weight. Packages of the dry, free-fl owing aspartame are required to prominently display the sweetening equivalence in teaspoons of sugar.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P304+P340-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| WGK Germany | 2 |
| RTECS | WM3407000 |
| TSCA | Yes |
| HS Code | 29242990 |
| Toxicity | TDLo orl-wmn: 3710 mg/kg:SKN AIMEAS 104,207,86 |
