N-Acetyl-L-Proline , 98% , 68-95-1

CAS NO.：68-95-1

Empirical Formula: C7H11NO3

Molecular Weight: 157.17

MDL number: MFCD00020837

EINECS: 200-698-9

PRODUCT Properties

• Melting point: 115-117 °C
• alpha: -86 º (c=1 EtOH)
• Boiling point: 366.2±35.0 °C(Predicted)
• Density: 1.274±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
• pka: 3.69±0.20(Predicted)
• form: Powder
• color: White to off-white
• BRN: 83200
• InChI: InChI=1S/C7H11NO3/c1-5(9)8-4-2-3-6(8)7(10)11/h6H,2-4H2,1H3,(H,10,11)/t6-/m0/s1
• InChIKey: GNMSLDIYJOSUSW-LURJTMIESA-N
• SMILES: C(O)(=O)[C@@H]1CCCN1C(C)=O

Description and Uses

N-Acetyl-L-proline (NALP) is an N-acetyl derivative of L-proline, which has wide application in medicine and is commonly utilized as a biologically active supplement. It can also act as an intermediate for synthesizing pharmaceuticals for preventing and treating some disorders and syndromes associated with the nervous, vascular, musculoskeletal, or cutaneous systems. In laboratories, it could play the role of a simple model for the secondary structure of proline-containing peptides. NALP can be acetylated from L-proline via a standard method, in the environment of acetic acid, or by the action of acetic anhydride on aqueous solutions of the products of the alkaline hydrolysis of gelatin followed by extraction. However,  these methods may result in the production of many byproducts[1]. 

N-Acetyl-L-proline is an aminoacid used in the synthesis of pharmaceutical compounds useful in preventing and treating disorders and syndromes associated with the nervous, vascular, musculoskeletal, o r cutaneous systems.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29339900