N-(2-Acetamido)iminodiacetic acid , 98% , 26239-55-4

Synonym(s):
N-(2-Acetamido)iminodiacetic acid;N-(Carbamoylmethyl)iminodiacetic acid;N-(2-Acetamido)-iminodiacetic acid

CAS NO.：26239-55-4

Empirical Formula: C6H10N2O5

Molecular Weight: 190.15

MDL number: MFCD00008031

EINECS: 247-530-0

PRODUCT Properties

• Melting point: 219 °C (dec.)(lit.)
• Boiling point: 325.64°C (rough estimate)
• Density: 1.4957 (rough estimate)
• vapor pressure: 0Pa at 25℃
• refractive index: 1.5010 (estimate)
• storage temp.: room temp
• solubility: 1 M NaOH: 0.05 M at 20 °C, clear, colorless
• form: Powder
• color: White to almost white
• PH: 1.5-3.0 (25℃, 0.01M in H2O)
• pka: 6.6(at 25℃)
• PH Range: 6.0 - 7.2
• Water Solubility: soluble
• λmax: λ: 260 nm Amax: 0.20; λ: 280 nm Amax: 0.05
• Merck: 14,147
• BRN: 1787181
• InChIKey: QZTKDVCDBIDYMD-UHFFFAOYSA-N
• LogP: -3.12 at 20℃

Description and Uses

N-(2-Acetamido)iminodiacetic acid is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.

N-(2-Acetamido)iminodiacetic acid (ADA) could prevents oxidation and irreversible denaturation of proteins while conducting gel electrophoresis. Furthermore studies suggest that ADA interferes with BCA and Lowry protein assays. Also ADA often chelates metal ions such as Mn(II), Cu(II), Ni(II), Zn(II), and Co(II) in a 2:1 at or below physiological pH values. Moreover, ADA is soluble in sodium hydroxide and absorbs UV radiation in the range below 260nm.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P501
• Safety Statements: 24/25
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• HS Code: 29241900