Home Categories Organic Chemistry N-(2-Acetamido)iminodiacetic acid
A0662612

N-(2-Acetamido)iminodiacetic acid , 98% , 26239-55-4

Synonym(s):
N-(2-Acetamido)iminodiacetic acid;N-(Carbamoylmethyl)iminodiacetic acid;N-(2-Acetamido)-iminodiacetic acid

CAS NO.:26239-55-4

Empirical Formula: C6H10N2O5

Molecular Weight: 190.15

MDL number: MFCD00008031

EINECS: 247-530-0

Pack Size Price Stock Quantity
25G RMB39.20 In Stock
100G RMB79.20 In Stock
500G RMB309.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 219 °C (dec.)(lit.)
Boiling point: 325.64°C (rough estimate)
Density  1.4957 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.5010 (estimate)
storage temp.  room temp
solubility  1 M NaOH: 0.05 M at 20 °C, clear, colorless
form  Powder
color  White to almost white
PH Range 6.0 - 7.2
PH 1.5-3.0 (25℃, 0.01M in H2O)
pka 6.6(at 25℃)
Water Solubility  soluble
λmax λ: 260 nm Amax: 0.20
λ: 280 nm Amax: 0.05
Merck  14,147
BRN  1787181
InChIKey QZTKDVCDBIDYMD-UHFFFAOYSA-N
LogP -3.12 at 20℃
CAS DataBase Reference 26239-55-4(CAS DataBase Reference)
EPA Substance Registry System Glycine, N-(2-amino-2-oxoethyl)-N-(carboxymethyl)- (26239-55-4)

Description and Uses

N-(2-Acetamido)iminodiacetic acid is a zwitterionic buffer used in biochemistry and molecular biology. It is one of the Good buffers developed in the 1960′s to provide buffers in the pH range of 6.15 - 8.35 for wide applicability to biochemical studies. The pioneering publication by Good and co-workers describes the synthesis of ADA and its physical properties. The useful range of ADA buffer in aqueous solution is 6.0 - 7.2.

N-(2-Acetamido)iminodiacetic acid (ADA) could prevents oxidation and irreversible denaturation of proteins while conducting gel electrophoresis. Furthermore studies suggest that ADA interferes with BCA and Lowry protein assays. Also ADA often chelates metal ions such as Mn(II), Cu(II), Ni(II), Zn(II), and Co(II) in a 2:1 at or below physiological pH values. Moreover, ADA is soluble in sodium hydroxide and absorbs UV radiation in the range below 260nm.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Safety Statements  24/25
WGK Germany  3
TSCA  Yes
HazardClass  IRRITANT
HS Code  29241900

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