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A0519256

4-AminobutyricAcid , Cosmetics , 56-12-2

Synonym(s):
GABA;4-Aminobutanoic acid;gamma-Aminobutyric acid;γ-Aminobutyric acid;Piperidinic acid

CAS NO.:56-12-2

Empirical Formula: C4H9NO2

Molecular Weight: 103.12

MDL number: MFCD00008226

EINECS: 200-258-6

Pack Size Price Stock Quantity
1g RMB31.20 In Stock
5g RMB111.20 In Stock
25g RMB391.20 In Stock
250mg RMB1039.20 In Stock
100g RMB1119.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 195 °C (dec.) (lit.)
Boiling point: 248.0±23.0 °C(Predicted)
Density  1.2300 (estimate)
refractive index  1.4650 (estimate)
FEMA  4288 | 4-AMINOBUTYRIC ACID
storage temp.  2-8°C
solubility  H2O: 1 M at 20 °C, clear, colorless
form  Powder
pka 4.031(at 25℃)
color  White to almost white
Odor at 1.00 % in propylene glycol. savory meaty
Odor Type meaty
Water Solubility  SOLUBLE
Merck  14,430
JECFA Number 1771
BRN  906818
InChIKey BTCSSZJGUNDROE-UHFFFAOYSA-N
LogP -3.17

Description and Uses

4-Aminobutyric acid (GABA) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. Although chemically it is an amino acid, GABA is rarely referred to as such in the scientific or medical communities, because the term "amino acid," used without a qualifier, conventionally refers to the alpha amino acids, which GABA is not, nor is it ever incorporated into a protein. In spastic diplegia in humans, GABA absorption becomes impaired by nerves damaged from the condition's upper motor neuron lesion, which leads to hypertonia of the muscles signaled by those nerves that can no longer absorb GABA.

4-Aminobutyric acid is an important inhibitory neurotransmitter in the central nervous system, which has good water solubility and thermal stability. It has been confirmed that GABA, as a small molecular weight non protein amino acid, has edible safety and can be used in the production of beverages and other foods. Studies have shown that a certain amount of GABA can improve the body's sleep quality and reduce blood pressure.The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H332
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36
WGK Germany  2
RTECS  ES6300000
Hazard Note  Irritant
TSCA  Yes
HS Code  29224995

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