4-(Dibenzofuranyl)boronicacid , 99% , 100124-06-9

Synonym(s):
4-Dibenzofuranboronic acid

CAS NO.：100124-06-9

Empirical Formula: C12H9BO3

Molecular Weight: 212.01

MDL number: MFCD00092336

EINECS: 672-293-9

PRODUCT Properties

• Melting point: 286-291 °C (lit.)
• Boiling point: 438.5±37.0 °C(Predicted)
• Density: 1.34±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• pka: 8.04±0.30(Predicted)
• form: powder
• color: white to off-white
• BRN: 1645426
• InChIKey: ZXHUJRZYLRVVNP-UHFFFAOYSA-N
• CAS DataBase Reference: 100124-06-9(CAS DataBase Reference)

Description and Uses

Dibenzofuran-4-boronic acid (DBFBA) is a boronic acid that has been used as a cross-coupling agent in the Suzuki coupling reaction. It has been shown to have low efficiency, but advances in this area have been made through the use of methanol extraction and photophysical properties. DBFBA is often coupled with imidazole derivatives to form anti-inflammatory compounds. The bond cleavage and hydrogen bonding properties of DBFBA make it a good target for drug synthesis.

Dibenzofuran-4-boronic acid is a water-soluble boronic acid, and the boronic acid molecule is a very useful functional group for the preparation of glycosensors. Water-soluble boronic acids that change their fluorescence properties upon binding to sugars are particularly useful as reporter units for carbohydrate fluorescence sensors. Dibenzofuran-4-boronic acid displays distinctive fluorescence changes at three wavelengths when bound to sugars under near-physiological conditions^[1].

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 37/39-26-24/25
• WGK Germany: 3
• TSCA: No
• HazardClass: IRRITANT
• HS Code: 29321900