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A0276456

Fosinopril-d5SodiumSalt

Synonym(s):
Fosinopril;Monopril;Secorvas;Staril;(2S,4S)-4-Cyclohexyl-1-(2-{[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylic acid

CAS NO.:

Empirical Formula: C30H46NNaO7P

Molecular Weight: 586.65

MDL number: MFCD00897699

EINECS: 1312995-182-4

Pack Size Price Stock Quantity
1mg RMB1624.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 196-198°C
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  H2O: >20mg/mL
form  powder
color  white to off-white

Description and Uses

Fosinopril sodium, an ester prodrug of fosinoprilat, is the first of a new generation of phosphinic acid ACE inhibitors indicated for the once-daily treatment of hypertension. Unlike captopril and lisinopril, it is reportedly effective in increasing the left ventricular peak filling rates and peak ejection rates in hypertensive patients at rest. Another advantage is that fosinopril sodium is metabolized equally by renal and hepatic routes, thereby avoiding the requirement to modify dosage in patients with renal insufficiency.

A labelled phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H319-H361d
Precautionary statements  P202-P264-P280-P305+P351+P338-P308+P313-P337+P313
WGK Germany  3
HS Code  2933995300

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