N-Methyl-N-trimethylsilylacetamide [Trimethylsilylating Agent] , >90.0%(GC) , 7449-74-3

Synonym(s):
MSA

CAS NO.：7449-74-3

Empirical Formula: C6H15NOSi

Molecular Weight: 145.27

MDL number: MFCD00040758

EINECS: 231-217-0

PRODUCT Properties

• Boiling point: 159-161 °C(lit.)
• Density: 0.904 g/mL at 20 °C(lit.)
• refractive index: n20/D 1.439
• Flash point: 48 °C
• storage temp.: -20°C
• pka: -0.11±0.70(Predicted)
• form: lyophilized powder
• color: Clear light yellow
• Specific Gravity: 0.906
• Sensitive: Moisture Sensitive
• BRN: 506975
• InChI: InChI=1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3
• InChIKey: QHUOBLDKFGCVCG-UHFFFAOYSA-N
• SMILES: C(N(C)[Si](C)(C)C)(=O)C
• CAS DataBase Reference: 7449-74-3(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, n-methyl-n-(trimethylsilyl)-(7449-74-3)
• EPA Substance Registry System: Acetamide, N-methyl-N-(trimethylsilyl)- (7449-74-3)

Description and Uses

N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following:

• Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique.
• Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.

Safety

• Symbol(GHS): GHS05,GHS02,GHS07
• Signal word: Warning
• Hazard statements: H314-H315-H319-H335-H226
• Precautionary statements: P261-P303+P361+P353-P305+P351+P338-P501a-P210-P233-P240-P241+P242+P243-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P370+P378-P403+P235-P405-P501
• Hazard Codes: Xi
• Risk Statements: 10-36/37/38
• Safety Statements: 37/39-16
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• F: 10-21
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• HS Code: 29319090