Hecogenin Acetate , >90.0%(HPLC) , 915-35-5
Synonym(s):
(−)-Hecogenin acetate
CAS NO.：915-35-5
Empirical Formula: C29H44O5
Molecular Weight: 472.66
MDL number: MFCD00005088
EINECS: 213-021-7
| Pack Size | Price | Stock | Quantity |
| 1g | RMB360.00 | In Stock |
|
| 5g | RMB952.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 246-248 °C (dec.)(lit.) |
| Boiling point: | 95-140 °C |
| Density | 1.15±0.1 g/cm3(Predicted) |
| refractive index | -4 ° (C=1, Dioxane) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, Heated) |
| form | Solid |
| color | White |
Description and Uses
Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.
Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 2937.29.9095 |
