Homatropine Methyl Bromide , 80-49-9

Synonym(s):
Homatropine methobromide;Homatropine methylbromide

CAS NO.：80-49-9

Empirical Formula: C17H24BrNO3

Molecular Weight: 370.28

MDL number: MFCD00050292

EINECS: 201-284-0

PRODUCT Properties

• Melting point: 192°C
• storage temp.: -20°C Freezer
• solubility: Freely soluble in water, soluble in ethanol 96 per cent
• form: Solid
• color: White to Off-White
• Merck: 14,4730
• CAS DataBase Reference: 80-49-9(CAS DataBase Reference)
• EPA Substance Registry System: Homatropine methylbromide (80-49-9)

Description and Uses

Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P301+P312+P330
• Risk Statements: 20/21/22
• Safety Statements: 22-26-36
• RIDADR: 1544
• WGK Germany: 3
• RTECS: MS9000000
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29399990
• Toxicity: LD50 in mice (mg/kg): 1400 orally, 60 i.p. (Cahen, Tvede)