PRODUCT Properties
| Melting point: | 161°C |
| Boiling point: | 276.04°C (rough estimate) |
| Density | 1.3682 (rough estimate) |
| vapor pressure | 0.007Pa at 25℃ |
| refractive index | 1.6500 (estimate) |
| solubility | almost transparency in hot Methanol |
| form | powder to crystal |
| pka | 0.99±0.10(Predicted) |
| Colour Index | 76030 |
| color | Yellow compound in hair dyes |
| Water Solubility | <0.1 g/100 mL at 20.5 ºC |
| BRN | 2094904 |
| LogP | 0.55 |
| CAS DataBase Reference | 5131-58-8(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Nitro-m-phenylenediamine (5131-58-8) |
Description and Uses
4-Nitro-1,3-diaminobenzene is a general chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of potent and selective Chk-1 inhibitors in the treatment of various cancers.
Safety
| Symbol(GHS) |    GHS07,GHS06,GHS08 |
| Signal word | Warning |
| Hazard statements | H315-H319-H301-H341 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P201-P301+P310a-P305+P351+P338-P405-P501a |
| Risk Statements | 22-36/38 |
| Safety Statements | 26-36/37/39 |
| RTECS | ST2910000 |
| TSCA | Yes |
| HS Code | 2921.51.5000 |
| Hazardous Substances Data | 5131-58-8(Hazardous Substances Data) |
| Toxicity | LD50 orl-rat: 4500 mg/kg GTPZAB 35(2),42,91 |
