Cholesterol-5α,6α-epoxide , >95.0%(GC) , 1250-95-9

Synonym(s):
5α,6α-Epoxycholestan-3β-ol;5α,6α-epoxy-cholesterol; 5α,6α-epoxy-5α-cholestan-3β-ol; cholesterol-5α,6α-epoxide; 110804

CAS NO.：1250-95-9

Empirical Formula: C27H46O2

Molecular Weight: 402.65

MDL number: MFCD00046980

EINECS: 215-007-6

PRODUCT Properties

• Melting point: 147 °C
• Boiling point: 464.74°C (rough estimate)
• Density: 0.9932 (rough estimate)
• refractive index: 1.4480 (estimate)
• storage temp.: -20°C
• solubility: Soluble in DMSO (up to 10 mg/ml) orin Ethanol (up to 10 mg/ml).
• form: solid
• pka: 15.20±0.70(Predicted)
• color: White
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Description and Uses

5α,6α-Epoxycholesterol (1250-95-9) is a naturally occurring metabolite of cholesterol.? It is a major oxysterol found in processed food1?and has been implicated in atherosclerosis2,3. 5α,6α-Epoxycholesterol has been found to be an endogenous ligand for LXR (EC50?= 76 nM).4

Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.

Safety

• WGK Germany: 3
• RTECS: FZ6360000