[Arg 8]-Vasopressin Acetate , >98.0%(HPLC) , 129979-57-3

Synonym(s):
β-Hypophamine;Antidiuretic hormone;Arginine vasopressin;AVP

CAS NO.：129979-57-3

Empirical Formula: C48H69N15O14S2

Molecular Weight: 1144.28

MDL number: MFCD00133939

PRODUCT Properties

• Melting point: 189 °C(dec.)
• storage temp.: −20°C
• solubility: Water: 1 mg/ml
• form: powder to crystal
• color: White to Light yellow
• Water Solubility: Water: 1 mg/ml

Description and Uses

Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V₁, with K_d values of 1.31 and 1.44 nM in A₇r₅ rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively. It also stimulates the intracellular release of calcium in A₇r₅ cells (EC₅₀ = 5 nM). In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H332
• Precautionary statements: P261-P271-P304+P340-P312
• Hazard Codes: Xn
• Risk Statements: 20
• Safety Statements: 36
• WGK Germany: 3
• F: 3-10
• HS Code: 2937.19.0000