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S8950314

≥98%(HPLC),powder , 218137-86-1

Synonym(s):
4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid;C 75;C-75

CAS NO.:218137-86-1

Empirical Formula: C14H22O4

Molecular Weight: 254.32

MDL number: MFCD03265452

Pack Size Price Stock Quantity
5mg RMB3004.60 In Stock
25mg RMB12006.30 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 432.1±45.0 °C(Predicted)
Density  1.08±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: 18 mg/mL
pka 3.08±0.40(Predicted)
form  solid
color  off-white

Description and Uses

C75 has been used:

  • as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
  • as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
  • as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3

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