33386-08-2

Synonym(s):
Buspirone hydrochloride;N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride

CAS NO.：33386-08-2

Empirical Formula: C21H32ClN5O2

Molecular Weight: 421.96

MDL number: MFCD00078569

EINECS: 251-489-4

PRODUCT Properties

• Melting point: 201.5-202.50C
• Flash point: 9℃
• storage temp.: 2-8°C
• solubility: Freely soluble in water and in methanol, practically insoluble in acetone.
• form: Solid
• color: White to off-white
• Water Solubility: Soluble in methanol (50 mg/ml), water (partly), DMSO (100 mM).
• CAS DataBase Reference: 33386-08-2(CAS DataBase Reference)

Description and Uses

Buspirone hydrochloride is an anxiolytic agent indicated for the management of anxiety disorders with or without accompanying depression. In contrast to the benzodiazepines, buspirone does not interact with alcohol, and lacks sedative, anticonvulsant, and muscle relaxant effects, and abuse potential.

anxiolitic;serotonin receptor agonist

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P264-P270-P301+P310-P405-P501
• Hazard Codes: T,Xn,F
• Risk Statements: 25-36/37/38-20/21/22-39/23/24/25-23/24/25-11
• Safety Statements: 45-36-26-36/37-16
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: CL9915000
• HazardClass: 6.1
• HS Code: 29335995
• Toxicity: LD50 i.p. in rats: 136 mg/kg (Allen)