PRODUCT Properties
| Melting point: | 172°C |
| Boiling point: | 276.07°C (rough estimate) |
| Density | 1.2583 (rough estimate) |
| refractive index | 1.5872 (estimate) |
| pka | pKa 6.820± 0.005(H2O,t = 25.0,Iundefined) (Uncertain) |
| Water Solubility | 4.8mg/L(22.5 ºC) |
| BCS Class | 3 |
| CAS DataBase Reference | 86-54-4 |
| IARC | 3 (Vol. 24, Sup 7) 1987 |
| NIST Chemistry Reference | 1(2H)-phthalazinone, hydrazone(86-54-4) |
| EPA Substance Registry System | Hydralazine (86-54-4) |
Description and Uses
Cross-reactions between hydrazine derivatives occur. Hydralazine may sometimes cause flushing and reversible Lupus erythematosis
Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310+P330-P405-P501 |
| Toxicity | LD50 in mice, rats (mg/kg): 122, 90 orally; 101, 40 i.p. (Dorigotti) |
