PRODUCT Properties
Melting point: | 172°C |
Boiling point: | 276.07°C (rough estimate) |
Density | 1.2583 (rough estimate) |
refractive index | 1.5872 (estimate) |
pka | pKa 6.820± 0.005(H2O,t = 25.0,Iundefined) (Uncertain) |
Water Solubility | 4.8mg/L(22.5 ºC) |
BCS Class | 3 |
Description and Uses
Cross-reactions between hydrazine derivatives occur. Hydralazine may sometimes cause flushing and reversible Lupus erythematosis
Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; semicarbazide-sensitive amine oxidase inhibitor. Antihypertensive
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P264-P270-P301+P310+P330-P405-P501 |
Toxicity | LD50 in mice, rats (mg/kg): 122, 90 orally; 101, 40 i.p. (Dorigotti) |