pharmaceuticalsecondarystandard,certifiedreferencematerial , 54143-56-5
Synonym(s):
N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate salt;Flecainide acetate salt
CAS NO.：54143-56-5
Empirical Formula: C19H24F6N2O5
Molecular Weight: 474.39
MDL number: MFCD00214290
EINECS: 258-997-5
| Pack Size | Price | Stock | Quantity |
| 500MG | RMB1598.69 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 145-147℃ |
| storage temp. | 2-8°C |
| solubility | Soluble in water and in anhydrous ethanol. It is freely soluble in dilute acetic acid and practically insoluble in dilute hydrochloric acid. |
| form | Solid |
| color | White |
| Water Solubility | Soluble in dilute acetic acid, dimethyl sulfoxide, ethanol, methanol and water. |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month. |
Description and Uses
Flecainide acetate (54143-56-5) is an open Na+?channel blocker that inhibits fast Na+?current in cardiac muscle in a use- and concentration-dependent manner.1?Orally-active class Ic antiarrhythmic agent2,3. Inhibits hERG potassium channels at clinically relevant concentrations.4
Flecainide acetate is used as a sodium channel blocker and as an anti-arrhythmic. In general, it is used to regulate heartbeats of the upper heart and lower heart chambers. It can also be used to slow down an overactive heart. It is also useful in the treatment of ventricular tachycardias and ventricular arrhythmias.
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302-H315-H319-H335-H360FD |
| Precautionary statements | P201-P202-P301+P312-P302+P352-P305+P351+P338-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38-63 |
| Safety Statements | 22-26-36/37/39-45-46 |
| RIDADR | 3249 |
| WGK Germany | - |
| RTECS | CV5792550 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2933399090 |
