S-Ketorolac , ≥98%(HPLC) , 66635-92-5
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB902.59 | In Stock |
|
| 25MG | RMB3635.10 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 160-167?C |
| Boiling point: | 493.2±40.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform: Slightly; Ethanol: >1mg/ml; Methanol: Slightly |
| form | A crystalline solid |
| pka | 4.29±0.20(Predicted) |
| color | White to off-white |
Description and Uses
(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac in a rat pain assay. (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac. Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation.
The R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
Safety
| Symbol(GHS) |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P405-P501 |
