Description and Uses
6-Hydroxy-2-(methylsulfanyl)-4-pyrimidinecarboxylic Acid has shown binding to HCR-13pf of MMP-13 hemopexin domain with no crossreactivity to MMP-1 and 8 which could serve as building block for development of drug for osteoarthritis (OA) and rheumatoid arthritis (RA). It can be useful in the structure-??activity relationship studies of pyrimidine base analogs as ligands of orotate phosphoribosyltransferase as well as allosteric inhibitors of a mammalian lectin.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HazardClass | IRRITANT |
