Pristinamycin , ≥98%(Assay)

CAS NO.：

Empirical Formula: C71H84N10O17

Molecular Weight: 1349.48

MDL number: MFCD01778146

EINECS: 234-244-6

PRODUCT Properties

• Melting point: 170-178℃
• storage temp.: Amber Vial, Hygroscopic, -20°C Freezer, Under inert atmosphere
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Solid
• color: Pale Yellow
• Stability: Hygroscopic, Light Sensitive
• EPA Substance Registry System: Virginiamycin (11006-76-1)

Description and Uses

Mikamycin was found in the culture broth of Streptomyces mitakaensis by Umezawa et al. of the University of Tokyo in 1956. It is a mixture of two components, A and B, showing synergistic effects on each other. Staphylomycin, which was found by De Somer of Leuven University in 1955, is a closely related compound. Mikamycin shows strong activity against grampositive bacteria, including strains resistant to other antibiotics. It has been used topically to treat Staphylococcus or Streptococcusinfections of the skin, including burns.

Virginiamycin complex is defined as a mixture of 75% ostreogrycin A (virginiamycin M1) and 25% virginiamycin S1, together with the less abundant S analogues. As the two major components have quite different solubilities, these proportions are not readily achieved or used. BioAustralis has isolated and re-combined the individual components to provide the defined components of virginiamycin complex. The composition of the complex is important as Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Safety

• Symbol(GHS): GHS07,GHS05
• Signal word: Danger
• Hazard statements: H302-H317-H318
• Precautionary statements: P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P280-P305+P351+P338-P310
• HS Code: 2941900000
• Hazardous Substances Data: 11006-76-1(Hazardous Substances Data)