S2569949
Buspironehydrochloride , PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial , 33386-08-2
Synonym(s):
Buspirone hydrochloride;N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride
CAS NO.:33386-08-2
Empirical Formula: C21H32ClN5O2
Molecular Weight: 421.96
MDL number: MFCD00078569
EINECS: 251-489-4
Pack Size | Price | Stock | Quantity |
500mg | RMB3197.07 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 201.5-202.50C |
Flash point: | 9℃ |
storage temp. | 2-8°C |
solubility | Freely soluble in water and in methanol, practically insoluble in acetone. |
form | Solid |
color | White to off-white |
Water Solubility | Soluble in methanol (50 mg/ml), water (partly), DMSO (100 mM). |
Description and Uses
Buspirone hydrochloride is an anxiolytic agent indicated for the management of anxiety disorders with or without accompanying depression. In contrast to the benzodiazepines, buspirone does not interact with alcohol, and lacks sedative, anticonvulsant, and muscle relaxant effects, and abuse potential.
anxiolitic;serotonin receptor agonist
Safety
Symbol(GHS) | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P264-P270-P301+P310-P405-P501 |
Hazard Codes | T,Xn,F |
Risk Statements | 25-36/37/38-20/21/22-39/23/24/25-23/24/25-11 |
Safety Statements | 45-36-26-36/37-16 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | CL9915000 |
HazardClass | 6.1 |
HS Code | 29335995 |
Toxicity | LD50 i.p. in rats: 136 mg/kg (Allen) |