γ-Butyrolactone , ReagentPlus ,≥99% , 96-48-0
Synonym(s):
γ-Butyrolactone;γ-Hydroxybutyric acid lactone;4-Hydroxybutyric acid lactone;gamma-Butyrolactone;GBL
CAS NO.：96-48-0
Empirical Formula: C4H6O2
Molecular Weight: 86.09
MDL number: MFCD00005386
EINECS: 202-509-5
PRODUCT Properties
| Melting point: | -45 °C (lit.) |
| Boiling point: | 204-205 °C (lit.) |
| Density | 1.12 g/mL at 25 °C (lit.) |
| vapor density | 3 (vs air) |
| vapor pressure | 1.5 mm Hg ( 20 °C) |
| FEMA | 3291 | 4-HYDROXYBUTANOIC ACID LACTONE |
| refractive index | n |
| Flash point: | 209 °F |
| storage temp. | 2-8°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 1 mg/ml |
| color | Clear colorless |
| PH Range | 4 at 100 g/l at 20 °C |
| Odor | at 100.00 %. creamy oily fatty caramel |
| Odor Type | creamy |
| explosive limit | 16% |
| Water Solubility | MISCIBLE |
| Merck | 13,1596 |
| JECFA Number | 219 |
| BRN | 105248 |
| Dielectric constant | 40.960000000000001 |
| Stability: | Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents. |
| InChIKey | YEJRWHAVMIAJKC-UHFFFAOYSA-N |
| LogP | -0.566 at 25℃ |
Description and Uses
Dihydro-2(3H)-furanone. An endogenous neuroregulator made from gamma-amino butyrate and the precursor of gamma hydroxybutyrate. It causes selective increase of brain dopamine by inhibiting its release from nerve terminals. The compound has sedative properties at low doses and produces surgical anesthesia at high doses. It is also used as an industrial solvent and precursor.
r-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.
Safety
| Symbol(GHS) |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302-H318-H336 |
| Precautionary statements | P261-P264-P270-P280-P301+P312-P305+P351+P338 |
| Hazard Codes | Xn,F |
| Risk Statements | 22-36-67-41-20/21/22-11 |
| Safety Statements | 26-36-39-36/37-16 |
| WGK Germany | 1 |
| RTECS | LU3500000 |
| Autoignition Temperature | 851 °F |
| TSCA | Yes |
| HS Code | 29322980 |
| Toxicity | LD50 orally in rats: 17.2 ml/kg (Smyth) |
