Ouabain , PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial , 11018-89-6

Synonym(s):
1β,3β,5β,11α,14,19-Hexahydroxycard-20(22)-enolide 3-(6-deoxy-α-L-mannopyranoside);Acocantherine;G-Strophanthin;Ouabain, Octahydrate - CAS 11018-89-6 - Calbiochem;Strophanthin G

CAS NO.：11018-89-6

Empirical Formula: C29H60O20

Molecular Weight: 728.77

MDL number: MFCD00149240

EINECS: 628-959-6

PRODUCT Properties

• Melting point: 260 °C
• storage temp.: room temp
• solubility: H₂O: 10 mg/mL cold
• form: powder
• color: white
• optical activity: [α]25/D 31 to 32.5° in H2O(lit.)
• Water Solubility: Soluble in water.
• Sensitive: Light Sensitive
• BRN: 101712
• Stability: Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
• EPA Substance Registry System: Card-20(22)-enolide, 3-[(6-deoxy-.alpha.-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, octahydrate, (1.beta.,3.beta.,5.beta.,11.alpha.)- (11018-89-6)

Description and Uses

Ouabain (11018-89-6) is a selective inhibitor of Na+ K+-ATPase isolated from Strophanthus gratus.1 Endogenous ouabain is found in human circulation.2 Displays cardiotonic and diuretic activity. May be used to induce hypertensive rat model.3?Cell permeable and active in vivo.

antiarrhythmic, cardiotonic, hypertensive, Na/K ATPase inhibitor

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301+H331-H373
• Precautionary statements: P301+P310+P330-P304+P340+P311-P314
• Hazard Codes: T
• Risk Statements: 23/25-33
• Safety Statements: 45
• RIDADR: UN 1544 6.1/PG 1
• WGK Germany: 3
• RTECS: RN3850000
• F: 8
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29389090