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S0852849

Maslinicacid , analyticalstandard , 4373-41-5

Synonym(s):
2α,3β-Dihydroxyolean-12-en-28-oic acid;2α-Hydroxyoleanolic acid;Crategolic acid

CAS NO.:4373-41-5

Empirical Formula: C30H48O4

Molecular Weight: 472.7

MDL number: MFCD00049293

Pack Size Price Stock Quantity
5mg RMB4685.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 267~269℃
Boiling point: 570.0±50.0 °C(Predicted)
Density  1.14±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  acetone: soluble1mg/mL, clear, colorless
pka 4.63±0.70(Predicted)
form  powder
color  white to off-white
Stability: Hygroscopic
InChIKey MDZKJHQSJHYOHJ-LLICELPBSA-N
SMILES [C@@]12(C)CC[C@@]3([H])C(C)(C)[C@@H](O)[C@H](O)C[C@]3(C)[C@@]1([H])CC=C1[C@]3([H])CC(CC[C@]3(C(=O)O)CC[C@@]21C)(C)C |&1:0,4,9,11,14,16,21,27,33,r|
LogP 7.870 (est)

Description and Uses

Maslinic acid (2-α,3-β-dihydroxyolean-12-en-28-oic acid) is a pentacyclic triterpene abundant in the cuticular lipid layer of olive fruits (Bianchi et al.,1994) .It is a compound of 30 carbon atoms grouped in five cycles that have several substitutes. Maslinic acid presents two hydroxyl groups bound to carbons 2 and 3,one carboxyl group bound to carbon 17, and a double bond between carbons 12 and 13.It is a highly hydrophobic compound of low water solubility. Maslinic acid is synthesized in plants via the cytoplasmic acetate/mevalonate pathway that leads to oxidosqualene (Seo et al., 1988).Oxidosqualene is cycled by various oxidosqualene cyclases, among them β-amyrin synthase, which catalyzes the transformation of oxydosqualene into β-amyrin (olean-12-3n-3β-ol). Afterwards,β-amyrin is converted by successive reactions into erythrodiol, oleanolic acid, and finally maslinic acid (Saimaru et al.,2007; Stiti et al.,2007).

Maslinic Acid is an apoptosis inducer in lung cancer cells, occuring under normoxic and hypoxic conditions.

Safety

Safety Statements  24/25
WGK Germany  3
HS Code  29181990

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