Maslinicacid , analyticalstandard , 4373-41-5
Synonym(s):
2α,3β-Dihydroxyolean-12-en-28-oic acid;2α-Hydroxyoleanolic acid;Crategolic acid
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB4685.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 267～269℃ |
| Boiling point: | 570.0±50.0 °C(Predicted) |
| Density | 1.14±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | acetone: soluble1mg/mL, clear, colorless |
| pka | 4.63±0.70(Predicted) |
| form | powder |
| color | white to off-white |
| Stability: | Hygroscopic |
| InChIKey | MDZKJHQSJHYOHJ-LLICELPBSA-N |
| SMILES | [C@@]12(C)CC[C@@]3([H])C(C)(C)[C@@H](O)[C@H](O)C[C@]3(C)[C@@]1([H])CC=C1[C@]3([H])CC(CC[C@]3(C(=O)O)CC[C@@]21C)(C)C |&1:0,4,9,11,14,16,21,27,33,r| |
| LogP | 7.870 (est) |
Description and Uses
Maslinic acid (2-α,3-β-dihydroxyolean-12-en-28-oic acid) is a pentacyclic triterpene abundant in the cuticular lipid layer of olive fruits (Bianchi et al.，1994) .It is a compound of 30 carbon atoms grouped in five cycles that have several substitutes. Maslinic acid presents two hydroxyl groups bound to carbons 2 and 3,one carboxyl group bound to carbon 17, and a double bond between carbons 12 and 13.It is a highly hydrophobic compound of low water solubility. Maslinic acid is synthesized in plants via the cytoplasmic acetate/mevalonate pathway that leads to oxidosqualene (Seo et al., 1988).Oxidosqualene is cycled by various oxidosqualene cyclases, among them β-amyrin synthase, which catalyzes the transformation of oxydosqualene into β-amyrin (olean-12-3n-3β-ol). Afterwards,β-amyrin is converted by successive reactions into erythrodiol, oleanolic acid, and finally maslinic acid (Saimaru et al.,2007; Stiti et al.,2007).
Maslinic Acid is an apoptosis inducer in lung cancer cells, occuring under normoxic and hypoxic conditions.
Safety
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29181990 |
| Hazardous Substances Data | 4373-41-5(Hazardous Substances Data) |
