M8154047
Vinflunine , 98% , 162652-95-1
CAS NO.:162652-95-1
Empirical Formula: C45H54F2N4O8
Molecular Weight: 816.94
MDL number: MFCD00938122
EINECS: 1806241-263-5
Pack Size | Price | Stock | Quantity |
5mg | RMB1747.20 | In Stock |
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others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Density | 1.39±0.1 g/cm3(Predicted) |
pka | 11.36±0.60(Predicted) |
CAS DataBase Reference | 162652-95-1(CAS DataBase Reference) |
Description and Uses
Vinflunine (also referred to as PM391) is a semisynthetic analog of the natural vinca alkaloids vinblastine and vincristine that was approved by the European Medicines Agency (EMEA) in 2009 for the treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regimen. Vinflunine is synthesized from anhydrovinblastine in a superacid media (HF-SbF5) and in the presence of a chlorinated solvent like CHCl3 or CCl4.