Fluprostenol(16-m-trifluoromethylphenoxytetranorProstaglandinF2α) , 98% , 54276-17-4

CAS NO.：54276-17-4

Empirical Formula: C23H29F3O6

Molecular Weight: 458.47

MDL number:

PRODUCT Properties

• Boiling point: 608.0±55.0 °C(Predicted)
• Density: 1.335±0.06 g/cm3(Predicted)
• storage temp.: -20°C Freezer
• solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Dichloromethane, Acetonitrile
• form: Solid
• pka: 4.76±0.10(Predicted)
• color: Colourless to Pale Yellow Oil

Description and Uses

Fluprostenol is a metabolically stable analog of PGF2α with potent FP receptor agonist activity. Fluprostenol is the optically active enantiomer of fluprostenol and would be expected to have twice the potency as the racemic mixture. Fluprostenol inhibits PGF2α binding to human and rat FP receptors with IC50 values of 3.5 and 7.5 nM, respectively. It is a much more potent luteolytic agent than PGF2α in rats with a minimum fully effective dose of 270 μg/kg to terminate pregnancy. It is also an effective inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 of 3-10 x 10?11 M.[Cayman Chemical]

Safety

• Symbol(GHS): GHS08,GHS06
• Signal word: Danger
• Hazard statements: H372-H370-H300+H310+H330
• Precautionary statements: P260-P264-P270-P307+P311-P321-P405-P501-P260-P264-P270-P314-P501
• HS Code: 2937500000