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M8112647

Fotemustine(S10036) , ≥98% , 92118-27-9

Synonym(s):
(+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate;Muphoran;Mustophorane;P-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl ester;S 10036

CAS NO.:92118-27-9

Empirical Formula: C9H19ClN3O5P

Molecular Weight: 315.69

MDL number: MFCD00866278

Pack Size Price Stock Quantity
10mg RMB472.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 85°
Density  1.37±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  H2O: ≥1mg/mL
form  powder
pka 9.47±0.46(Predicted)
color  light yellow
CAS DataBase Reference 92118-27-9(CAS DataBase Reference)

Description and Uses

Fotemustine is a new nitrosourea reportedly effective in the treatment of disseminated malignant melanoma, with only mild hematological toxicity. Response rate is generally lower in patients with colonic, breast, head and neck cancer.

Fotemustine is used in patients malignant gliomas to improve the efficacy of radiotherapy. Used in the treatment of glioblastomas.

Safety

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P281
Hazard Codes  Xn
Risk Statements  40
Safety Statements  36/37
WGK Germany  3
Hazardous Substances Data 92118-27-9(Hazardous Substances Data)

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