M8112647
Fotemustine(S10036) , ≥98% , 92118-27-9
Synonym(s):
(+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate;Muphoran;Mustophorane;P-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl ester;S 10036
CAS NO.:92118-27-9
Empirical Formula: C9H19ClN3O5P
Molecular Weight: 315.69
MDL number: MFCD00866278
Pack Size | Price | Stock | Quantity |
10mg | RMB472.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 85° |
Density | 1.37±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | H2O: ≥1mg/mL |
form | powder |
pka | 9.47±0.46(Predicted) |
color | light yellow |
Description and Uses
Fotemustine is a new nitrosourea reportedly effective in the treatment of disseminated malignant melanoma, with only mild hematological toxicity. Response rate is generally lower in patients with colonic, breast, head and neck cancer.
Fotemustine is used in patients malignant gliomas to improve the efficacy of radiotherapy. Used in the treatment of glioblastomas.