M8075847
MMP-9/MMP-13InhibitorI , 98% , 204140-01-2
Synonym(s):
MMP-9/MMP-13 Inhibitor I - CAS 204140-01-2 - Calbiochem;N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide
CAS NO.：204140-01-2
Empirical Formula: C25H25N3O6S
Molecular Weight: 495.55
MDL number: MFCD03453559
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB1983.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.364±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO or methanol |
| pka | 9.38±0.23(Predicted) |
| form | Solid |
| color | White to off-white |
| Sensitive | Light Sensitive |
Description and Uses
MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). It less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC50s = 43, 23, and 920 nM, respectively). MMP-9/MMP-13 inhibitor I has been used to elucidate the roles of MMPs in biological systems, including tumor cell invasion and pathogenesis of P. falciparum.
A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 and MMP-13
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |