Home Categories Analytical Chemistry 2-PalmitoylGlycerol
M8051647

2-PalmitoylGlycerol , 98% , 23470-00-0

CAS NO.:23470-00-0

Empirical Formula: C19H38O4

Molecular Weight: 330.5

MDL number: MFCD00273078

Pack Size Price Stock Quantity
5mg RMB1062.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 68-70°C
Boiling point: 387.92°C (rough estimate)
Density  0.9708 (rough estimate)
refractive index  1.4434 (estimate)
storage temp.  −20°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka 13.54±0.10(Predicted)
form  Solid
color  White to Off-White
BRN  1796692

Description and Uses

2-Arachidonoyl glycerol (2-AG; ) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release. 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.

A biomarker of metabolic responses to hepatotoxicants and carcinogens.

Safety

Hazard Codes  Xi
Risk Statements  43
Safety Statements  36/37
WGK Germany  3

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