GangliosideGD1bMixturesodiumsalt , 98% , 19553-76-5
Synonym(s):
Ganglioside GD1b, disialo
CAS NO.：19553-76-5
Empirical Formula: C84H148N4O40
Molecular Weight: 1854.08
MDL number: MFCD00466941
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB5384.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | −20°C |
| solubility | Chloroform:Methanol:DI Water (2:1:0.1): soluble |
| form | lyophilized powder |
Description and Uses
Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas. Ganglioside GD1b mixture contains ganglioside GD1b molecular species with C18:1 and C20:1 fatty acyl chains.
Ganglioside GD1b Disodium Salt (Bovine Brain) is a ganglioside, major constituents of neuronal cell membranes and endoplasmic reticulum that have been shown to modulate cell signal transduction.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| F | 10-21 |
| HS Code | 29400090 |
