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M8026747

ProstaglandinF2β(tromethaminesalt) , 98% , 89847-02-9

CAS NO.:89847-02-9

Empirical Formula: C24H45NO8

Molecular Weight: 475.62

MDL number: MFCD00135236

Pack Size Price Stock Quantity
1mg RMB1156.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

solubility  Acetone: >5 mg/ml (from PGF2a THAM); Acetonitrile: >5 mg/ml (from PGF2a THAM); DMSO: >50 mg/ml (from PGF2a THAM); Ethanol: >50 mg/ml (from PGF2a THAM); Methanol: >100 mg/ml (from PGF2a THAM); PBS pH 7.2: >25 mg/ml (from PGF2a THAM)
form  A crystalline solid

Description and Uses

Prostaglandin F (PGF) (tromethamine salt) is a derivative of PGF with increased water solubility. PGF is the 9β-hydroxy stereoisomer of PGF2α . It is much less active than PGF in antifertility and bronchoconstrictor activities. PGF exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF.

(5R)-Dinoprost tromethamine (Prostaglandin F2β tromethamine) is a metabolite produced by the metabolism of arachidonic acid cyclooxygenase. (5R)-Dinoprost tromethamine induces dose-dependent release of hexosaccharide containing mucin[1][2].

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H360
Precautionary statements  P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501

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