M8025847
OligomycinC , ≥95% , 11052-72-5
CAS NO.:11052-72-5
Empirical Formula: C45H74O10
Molecular Weight: 775.06
MDL number: MFCD32182610
EINECS: 234-276-0
Pack Size | Price | Stock | Quantity |
1mg | RMB5644.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 876.2±65.0 °C(Predicted) |
Density | 1.091 g/cm3 |
storage temp. | −20°C |
solubility | Soluble in DMSO |
form | White to off-white powder. |
pka | 13.49±0.70(Predicted) |
Merck | 13,6902 |
Description and Uses
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin C is a minor component of the oligomycin complex that acts as an inhibitor of the mitochondrial F1FO-ATP synthase. Inhibition of the ATP synthase by oligomycins leads to cell death.
Oligomycin C is an ATP synthetase and RVD inhibitor.