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M8025847

OligomycinC , ≥95% , 11052-72-5

CAS NO.:11052-72-5

Empirical Formula: C45H74O10

Molecular Weight: 775.06

MDL number: MFCD32182610

EINECS: 234-276-0

Pack Size Price Stock Quantity
1mg RMB5644.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 876.2±65.0 °C(Predicted)
Density  1.091 g/cm3
storage temp.  −20°C
solubility  Soluble in DMSO
form  White to off-white powder.
pka 13.49±0.70(Predicted)
Merck  13,6902

Description and Uses

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin C is a minor component of the oligomycin complex that acts as an inhibitor of the mitochondrial F1FO-ATP synthase. Inhibition of the ATP synthase by oligomycins leads to cell death.

Oligomycin C is an ATP synthetase and RVD inhibitor.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P271
Hazard Codes  Xn
Risk Statements  22
RIDADR  2811
RTECS  RK3335000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2941900000
Toxicity LD50 ipr-mus: 8300 mg/kg JACSAT 80,6092,1958

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