M8015147
O-DesmethylMetoprolol , 98% , 62572-94-5
Pack Size | Price | Stock | Quantity |
1mg | RMB920.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 70-720C |
Boiling point: | 424.6±40.0 °C(Predicted) |
Density | 1.085±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) |
form | Solid |
pka | 13.88±0.20(Predicted) |
color | White to Off-White |
Description and Uses
O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol . It is formed by metabolism of metoprolol by the cytochrome P450 (CYP) isoform CYP2D6 in vivo.
O-Desmethyl Metoprolol (Metoprolol EP Impurity H) is a metabolite of Metoprolol.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Toxicity | LD50 intravenous in dog: 150mg/kg |