PRODUCT Properties
Melting point: | 235℃ |
alpha | D +140° (c = 0.8) |
Boiling point: | 652.1±55.0 °C(Predicted) |
Density | 1.61±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Chloroform: soluble; DMSO: soluble; Ethyl Acetate: soluble; Methanol: soluble |
form | A solid |
pka | 5.17±0.60(Predicted) |
color | Yellow |
Description and Uses
(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.
Geodin is an inhibitor of plasminogen activator inhibitor (PAI-1).
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302+H312+H332 |
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501 |