M7979847
CholicAcid7-sulfate , 98% , 60320-05-0
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB1937.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 1 mg/ml; DMSO: 0.3 mg/ml; PBS (pH 7.2): 1 mg/ml |
| form | A crystalline solid |
| pka | -3.54±0.18(Predicted) |
| color | White to off-white |
Description and Uses
Cholic acid 7-sulfate is a metabolite of the primary bile acid cholic acid . It is produced by conjugation of a sulfate group with the hydroxy group at position 7 of cholic acid in the liver and gut. Fecal levels of cholic acid 7-sulfate are increased in male, but not female, mice fed a diet supplemented with cholic acid or chenodeoxycholic acid .
Cholic acid 7-sulfate (7-Sulfocholic acid), a metabolite of Cholic acid, is a Takeda G-protein receptor 5 (TGR5) agonist. Cholic acid 7-sulfate can increase Tgr5 expression and induce GLP-1 secretion[1].