PRODUCT Properties
Melting point: | 89-91 °C |
Boiling point: | 422.8±45.0 °C(Predicted) |
Density | 1.203±0.06 g/cm3(Predicted) |
storage temp. | Store at -20°C |
form | Solid |
pka | 8.45±0.20(Predicted) |
color | White to yellow |
LogP | 3.342 (est) |
Description and Uses
Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 μM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 μM and shows a high selectivity index for hMAO-A versus hMAO-B[1].