Azido-PEG1-C1-Boc , ≥95% , 1820717-35-8

CAS NO.：1820717-35-8

Empirical Formula: C8H15N3O3

Molecular Weight: 201.223

MDL number: MFCD27635154

PRODUCT Properties

• solubility: Soluble in DCM, DMF

Description and Uses

Azido-PEG1-CH2CO2-t-Bu is a azide (N3) containing PEG linker.The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.