Fluorescein-thiourea-PEG2-azide , ≥95% , 1146195-72-3
CAS NO.:1146195-72-3
Empirical Formula: C27H25N5O7S
Molecular Weight: 563.59
MDL number: MFCD32173718
Pack Size | Price | Stock | Quantity |
25mg | RMB2924.00 | In Stock |
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others | Enquire |
PRODUCT Properties
solubility | Soluble in DMSO, DMF, DCM |
Description and Uses
Fluorescein-PEG2-azide is a green emitting fluorescent dye derivitative with excitation/emmission maximum 494/517 nm containing an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding.
Fluorescein-thiourea-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fluorescein-thiourea-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.