Benzyl-PEG2-azide , 97% , 1260001-87-3

CAS NO.：1260001-87-3

Empirical Formula: C11H15N3O2

Molecular Weight: 221.26

MDL number: MFCD28064332

PRODUCT Properties

• form: Liquid
• color: Colorless to light yellow

Description and Uses

Benzyl-PEG2-azide is a PEG linker with an acid labile, benzyl protecting group. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Benzyl-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Benzyl-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.