M7285558
UCN-02 , ≥98% , 121569-61-7
Pack Size | Price | Stock | Quantity |
500μg | RMB1560.00 | In Stock |
|
1mg | RMB2166.40 | In Stock |
|
5mg | RMB8664.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 705.7±60.0 °C(Predicted) |
Density | 1.63±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
form | solution in ethanol. |
pka | 12.25±0.70(Predicted) |
color | Colorless to light yellow |
Description and Uses
UCN-02 is a derivative of staurosporine and a stereoisomer of UCN-01 first isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. UCN-02 inhibits protein kinase C with a slightly reduced potency than UCN-01 (IC50 = 62 and 4.1 nM, for UNC-02 and UCN-01, respectively) and is cytotoxic to the growth of HeLa S3 cells.
UCN-02 is an antibiotic and an indolocarbazole isolated from a high staurosporine-producing?Streptomyces?culture. Related analogs of staurosporine which is non-specific protein kinase inhibitor.
Safety
Symbol(GHS) | GHS02 |
Signal word | Danger |