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M7285558

UCN-02 , ≥98% , 121569-61-7

CAS NO.:121569-61-7

Empirical Formula: C28H26N4O4

Molecular Weight: 482.53

MDL number: MFCD32174062

Pack Size Price Stock Quantity
500μg RMB1560.00 In Stock
1mg RMB2166.40 In Stock
5mg RMB8664.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 705.7±60.0 °C(Predicted)
Density  1.63±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in DMSO
form  solution in ethanol.
pka 12.25±0.70(Predicted)
color  Colorless to light yellow

Description and Uses

UCN-02 is a derivative of staurosporine and a stereoisomer of UCN-01 first isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. UCN-02 inhibits protein kinase C with a slightly reduced potency than UCN-01 (IC50 = 62 and 4.1 nM, for UNC-02 and UCN-01, respectively) and is cytotoxic to the growth of HeLa S3 cells.

UCN-02 is an antibiotic and an indolocarbazole isolated from a high staurosporine-producing?Streptomyces?culture. Related analogs of staurosporine which is non-specific protein kinase inhibitor.

Safety

Symbol(GHS) 
GHS02
Signal word  Danger

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