Okadaicacidammoniumsalt , ≥98% , 175522-42-6

CAS NO.：175522-42-6

Empirical Formula: C44H71NO13

Molecular Weight: 822.05

MDL number: MFCD00153856

PRODUCT Properties

• storage temp.: Freezer (-20°C)

Description and Uses

Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation[1][2].

Safety

• HS Code: 29189990