M7183958
Propargyl-PEG10-acid , 95% , 2055022-18-7
Pack Size | Price | Stock | Quantity |
250mg | RMB3184.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 593.9±50.0 °C(Predicted) |
Density | 1.124±0.06 g/cm3(Predicted) |
solubility | Soluble in Water, DMSO, DCM, DMF |
pka | 4.28±0.10(Predicted) |
form | Liquid
(Density: 1.124±0.06 g/cm3) |
color | Colorless to light yellow |
Description and Uses
Propargyl-PEG10-acid is a propargyl PEG linker with a terminal carboxylic acid. The terminal carboxylic acid forms amide bonds with primary amines; activators (EDC or HATU) will be needed. The propargyl group can react with azide-bearing compounds to form stable triazole bonds.
Propargyl-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG10-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.