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M7183958

Propargyl-PEG10-acid , 95% , 2055022-18-7

CAS NO.:2055022-18-7

Empirical Formula: C24H44O12

Molecular Weight: 524.6

MDL number: MFCD28976690

Pack Size Price Stock Quantity
250mg RMB3184.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 593.9±50.0 °C(Predicted)
Density  1.124±0.06 g/cm3(Predicted)
solubility  Soluble in Water, DMSO, DCM, DMF
pka 4.28±0.10(Predicted)
form  Liquid (Density: 1.124±0.06 g/cm3)
color  Colorless to light yellow

Description and Uses

Propargyl-PEG10-acid is a propargyl PEG linker with a terminal carboxylic acid. The terminal carboxylic acid forms amide bonds with primary amines; activators (EDC or HATU) will be needed. The propargyl group can react with azide-bearing compounds to form stable triazole bonds.

Propargyl-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG10-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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