M6243435
Verinurad(RDEA3170) , 99% , 1352792-74-5
Pack Size | Price | Stock | Quantity |
5mg | RMB900.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 204 - 207°C |
Boiling point: | 566.7±50.0 °C(Predicted) |
Density | 1.34±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 2.91±0.10(Predicted) |
form | Solid |
color | Off-White to Pale Brown |
Description and Uses
Verinurad is an inhibitor of urate anion transporter 1 (URAT1; IC50 = 0.025 μM for the human transporter). It is selective for human URAT1 over rat URAT1 (IC50 = 41 μM), as well as human organic anion transporter 1 (OAT1) and OAT4 (IC50s = 4.6 and 5.9 μM, respectively).
Verinurad is a second generation selective uric acid reabsorption inhibitor.