M5973735
TAK-632 , >98% , 1228591-30-7
CAS NO.:1228591-30-7
Empirical Formula: C27H18F4N4O3S
Molecular Weight: 554.52
MDL number: MFCD26960965
EINECS: 200-256-5
Pack Size | Price | Stock | Quantity |
10mg | RMB604.80 | In Stock |
|
50mg | RMB2721.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Density | 1.52±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | ≥27.75 mg/mL in DMSO; insoluble in H2O; ≥2.23 mg/mL in EtOH with gentle warming and ultrasonic |
form | solid |
pka | 9.59±0.70(Predicted) |
color | White to off-white |
Description and Uses
TAK-632 is a selective pan-RAF inhibitor. It exhibits antitumor activity by inducing RAF dimerization but inhibiting its kinase activity in BRAF- and NRAS-mutated with acquired resistance to BRAF inhibitor in human and mouse melanoma cell.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |