Home Categories Biochemical Engineering TAK-632
M5973735

TAK-632 , >98% , 1228591-30-7

CAS NO.:1228591-30-7

Empirical Formula: C27H18F4N4O3S

Molecular Weight: 554.52

MDL number: MFCD26960965

EINECS: 200-256-5

Pack Size Price Stock Quantity
10mg RMB604.80 In Stock
50mg RMB2721.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Density  1.52±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  ≥27.75 mg/mL in DMSO; insoluble in H2O; ≥2.23 mg/mL in EtOH with gentle warming and ultrasonic
form  solid
pka 9.59±0.70(Predicted)
color  White to off-white

Description and Uses

TAK-632 is a selective pan-RAF inhibitor. It exhibits antitumor activity by inducing RAF dimerization but inhibiting its kinase activity in BRAF- and NRAS-mutated with acquired resistance to BRAF inhibitor in human and mouse melanoma cell.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

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