Testosteroneundecanoate , 98% , 5949-44-0

CAS NO.：5949-44-0

Empirical Formula: C30H48O3

Molecular Weight: 456.71

MDL number: MFCD00468114

EINECS: 227-712-6

PRODUCT Properties

• Melting point: 59-61°C
• Boiling point: 550.7±50.0 °C(Predicted)
• Density: 1.03±0.1 g/cm3(Predicted)
• storage temp.: Controlled Substance, -20°C Freezer
• solubility: DMSO : 10 mg/mL (21.90 mM; Need ultrasonic and warming)
• form: Solid
• color: White to Off-White
• InChIKey: UDSFVOAUHKGBEK-JCROKFDDNA-N
• SMILES: C[C@]12CCC(=O)C=C1CC[C@@]1([H])[C@]3([H])CC[C@H](OC(=O)CCCCCCCCCC)[C@@]3(C)CC[C@]21[H] |&1:1,10,12,16,30,34,r|
• CAS DataBase Reference: 5949-44-0(CAS DataBase Reference)

Description and Uses

Testosterone undecanoate, sold under the brand names Andriol and Aveed among others, is an androgen and anabolic steroid (AAS) medication that is used mainly in the treatment of low testosterone levels in men. which includes hormone therapy for transgender men. It is taken by mouth or given by injection into muscle.
Testosterone Undecanoate is the undecanoate ester form of the androgen testosterone, with gonadotropin-secretory inhibiting and hormone replacement activity. As testosterone inhibits the secretion of gonadotropins from the pituitary gland, administration of testosterone decreases the secretion of luteinizing hormone (LH). By inhibiting LH secretion, the growth of Leydig cells, which are normally stimulated by LH to produce testosterone, may be suppressed. In addition, this agent promotes the maintenance of male sex characteristics and can be used for testosterone replacement in hypogonadal males.

Testosterone undecanoate is the ester prodrug of testosterone and has a midchain fatty acid at the 17Beta position. It is available as an intramuscular injection and as an oral capsule, and is indicated for treatment of testosterone deficiency. It should be noted that testosterone undecanoate is only indicated for treatment of hypogonadal conditions with structural or genetic etiologies and should not be used to manage "age-related hypogonadism".

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H351-H360-H302-H362
• Precautionary statements: P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313-P201-P202-P281-P308+P313-P405-P501