SchizandrolB , Analysis standard product, 98% , 58546-55-7
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB230.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 638.6±55.0 °C(Predicted) |
| Density | 1.28 |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 13.54±0.60(Predicted) |
| form | Solid |
| color | White to Off-White |
Description and Uses
Schisantherin B (STB) is a lignan originally isolated from S. sphenanthera fruit. It inhibits formation of advanced glycation end products (AGEs) in vitro. STB (0.1 mg/kg) decreases escape latency in the Morris water maze and increases spontaneous alternation in the Y-maze in a mouse model of Alzheimer''s disease induced by amyloid-β (1-42) . It increases glial expression of glutamate transporter 1 (GLP-1) and decreases immobility time in the forced swim test (FST) in mice, indicating antidepressant-like activity. STB also increases spontaneous alternation in the Y-maze in a mouse model of stress-induced short-term learning impairment induced by the FST.
Schisantherin B is a bioactive of lignans isolated from Schisandra chinesis which protect against cognitive deficits and neurodegeneration induced by Aβ1-42 in mice.
