Home Categories Analytical Chemistry OCHRATOXINB
M4676335

OCHRATOXINB , 99% , 4825-86-9

CAS NO.:4825-86-9

Empirical Formula: C20H19NO6

Molecular Weight: 369.37

MDL number: MFCD00133680

EINECS: 621-766-8

Pack Size Price Stock Quantity
5mg RMB6310.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 221° (van der Merwe)
alpha  D -35° (c = 0.15 in ethanol)
Boiling point: 632.4±55.0 °C(Predicted)
Density  1.361±0.06 g/cm3(Predicted)
Flash point: -11 °C
storage temp.  2-8°C
solubility  DMF: 10 mg/ml; DMSO: 15 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.50 mg/ml
form  A crystalline solid
pka 3.40±0.10(Predicted)
color  White to off-white
EPA Substance Registry System L-Phenylalanine, N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]- (4825-86-9)

Description and Uses

Ochratoxins are mycotoxins produced by Aspergillus and Penicillium species of fungi that contaminate foods. Ochratoxin A (OTA, ) is a chlorinated form with toxicity that targets the kidneys, causing nephropathy and renal adenomas. OTB is a non-chlorinated analog of OTA that has cytotoxic effects on kidney and liver cells in vitro but only minor effects in vivo, due to its rapid metabolism and excretion. OTB inhibits cell proliferation of human liver HepG2 cells at doses as low as 1 μg/ml but lacks the genotoxic activity of OTA, even at higher concentrations.

Ochratoxin B is the non-chlorinated analogue of the much more extensively studied ochratoxin A. It is co-produced by the same species of Aspergillus and Penicillium that are associated with food spoilage. Ochratoxin B has received little focused investigation and its mode of action and potential hazards have been inferred from ochratoxin A.

Safety

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302-H312-H319-H332
Precautionary statements  P210-P280-P305+P351+P338
Hazard Codes  Xn,T,F
Risk Statements  22-36/37/38-65-48/23/24/25-36/38-11-46-45-36-20/21/22
Safety Statements  26-36-45-16-53-36/37-62
RIDADR  UN 3462 6.1/PG 3
WGK Germany  3
RTECS  AY6825000
HazardClass  6.1(a)
PackingGroup  I
HS Code  39229000
Hazardous Substances Data 4825-86-9(Hazardous Substances Data)

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