Home Categories API Metergoline?
M4081835

Metergoline? , ≥99% , 17692-51-2

Synonym(s):
[(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester;N-CBZ-[(8β)-1,6-Dimethylergolin-8-yl]methylamine

CAS NO.:17692-51-2

Empirical Formula: C25H29N3O2

Molecular Weight: 403.52

MDL number: MFCD00153829

EINECS: 241-686-3

Pack Size Price Stock Quantity
50mg RMB1104.00 In Stock
100mg RMB1680.00 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 148-150 °C(lit.)
alpha  D28 -7 ±2°
Boiling point: 612.5±55.0 °C(Predicted)
Density  1.25±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  0.1 M HCl: 1.4 mg/mL
pka 12.45±0.46(Predicted)
form  solid
color  White
Merck  13,5962
Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethaqnol may be stored at -20°C for up to 2 month.
InChIKey WZHJKEUHNJHDLS-QTGUNEKASA-N
CAS DataBase Reference 17692-51-2(CAS DataBase Reference)

Description and Uses

Metergoline (17692-51-2) is an ergot alkaloid derivative acting as antagonist at serotonin 5HT1 and 5HT2 receptors1,2 and 5HT7 receptors3. A safe and effective agent for management of hyperprolactinemic amenorrhea and anovulation.4 Displays a long-lasting antidepressant effect in seasonal affective disorder.5

Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  36
WGK Germany  3
RTECS  FA1070000
Toxicity LD50 in mice (mg/kg): 85 i.p., 430 orally; in rats (mg/kg): >800 orally (Beretta)

RELATED PRODUCTS