MethylophiopogonanoneA , 96% , 74805-92-8
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1025.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 580.1±50.0 °C(Predicted) |
| Density | 1.410 |
| solubility | Soluble in chloroform and methanol; |
| form | powder |
| pka | 8.24±0.40(Predicted) |
| color | Light yellow |
| Water Solubility | insoluble in water |
Description and Uses
Methylophiopogonanone A is a homoisoflavonoid that has been found in O. japonicus roots and has diverse biological activities. It increases the uptake of rosuvastatin (Item Nos. 12029 | 18813) and atorvastatin in HEK293T cells expressing human organic anion transporting polypeptide 1B1 (OATP1B1; EC50s = 11.33 and 6 μM, respectively). Methylophiopogonanone A scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals in cell-free assays. In vivo, methylophiopogonanone A (10 mg/kg) decreases body weight gain and reduces serum and hepatic lipid levels in a rat model of high-fat diet-induced hyperlipidemia. It also reduces infarct size and myocardial apoptosis in mouse model of ischemia-reperfusion injury induced by transient occlusion of the left anterior descending coronary artery.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
