M3632257
WRG-28 , ≥98% , 1913291-02-7
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1520.00 | In Stock |
|
| 25mg | RMB5280.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 603.4±65.0 °C(Predicted) |
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 15.62 mg/mL (38.06 mM) |
| pka | 11.55±0.50(Predicted) |
| form | Solid |
| color | Pink to red |
Description and Uses
WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice[1][2].
